Sinusoidal Cells in Liver Diseases: Role in their Pathophysiology, Diagnosis, and Treatment

Description

By Jordi Gracia-Sancho BSc PhD
Sinusoidal Cells in Liver Diseases: Role in their Pathophysiology, Diagnosis, and Treatment provides a state-of-the-art review on recent advances surrounding the role of liver sinusoidal cells (LSECs, HSCs, macrophages, and other non-parenchymal cells) in acute and chronic liver diseases. Coverage emphasizes disease pathophysiology, novel mechanisms, unmet clinical questions, development of biomarkers, and treatment opportunities. By focusing on the role of sinusoidal cells in human liver diseases, this reference provides a comprehensive overview of the role of sinusoidal cells in acute and chronic liver diseases, in its pathophysiology and mechanisms, and in the development of novel biomarkers and new therapeutics. Cells of the liver vasculature play an essential role in the pathophysiology of acute and chronic liver diseases and are considered key therapeutic targets to treat most of human hepatopathies. Coverage in this reference includes the phenotypic changes occurring in liver vascular cells and how cells contribute to the development of microcirculatory dysfunction, fibrosis, inflammation, and liver failure.

Provides a comprehensive update on the role of sinusoidal cells in acute and chronic liver diseases
Covers our current understanding of the role of sinusoidal cells as therapeutic targets to improve liver diseases
Presents the latest research in the development of novel biomarkers of liver diseases that derive from sinusoidal cells

 
Product Details

Publisher ‏ : ‎ Academic Press; 1st edition (May 3, 2024)
Language ‏ : ‎ English
Paperback ‏ : ‎ 562 pages
ISBN-10 ‏ : ‎ 0323952623
ISBN-13 ‏ : ‎ 978-0323952620